Ghetts was a member of grime collective NASTY Crew, however he left, saying that things had gone "pear shaped" This quote needs a citation] due to the number of people in the group. He later went on to create the grime collective The Movement, including Devlin, Wretch 32, Scorcher, Mercston, Lightning, and DJ Unique. Ghetts has made a number of well-known songs within the UK grime scene. In 2008, Ghetts was nominated for a BET Award for Best International Act: UK along with Chipmunk, Giggs, and Skepta. In the end, Giggs took the award home.

In October 2020, Ghetts collaborated with Fraser T. Smith in the production of Smith's debut album "12 Questions".